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LabCyte References

  • EPI-MODEL References
  • CORNEA-MODEL References

EPI-MODEL References


Title An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens.
Author
(affiliation)
Saito K, Takenouchi O, Nukada Y, Miyazawa M, Sakaguchi H
(Kao Corporation, R&D, Safety Science Research)
Journal Toxicol In Vitro. 2016 Dec 10;40:11-25
PMID 27965148

Title Hand hygiene using a new hand-cleansing formulation without sanitizers: Effect on Staphylococcus aureus removal and recovery of properties against skin damage
Author
(affiliation)
Asaoka K1,2, Endo S1, Suzuki Y1, Komuro S3, Nemoto T4, Kaku M1
(1Tohoku University, 2Kao Corporation, 3Geriatric Health Services Facility "Cosmos", 4Izumi Orthopedic Hospital)
Journal Am J Infect Control. 2016 Aug 1;44(8):e129-32
PMID 27207159

Title Esterase activity and intracellular localization in reconstructed human epidermal cultured skin models.
Author
(affiliation)
Tokudome Y. Katayanagi M. Hashimoto F.
(Josai University)
Journal Annals of Dermatology 27 (3) 269-274, 2015
PMID 26082583

Title In vitro analysis of the effect of alkyl-chain length of anionic surfactants on the skin by using a reconstructed human epidermal model.
Author
(affiliation)
Yamaguchi F, Watanabe S, Harada F, Miyake M, Yoshida M, Okano T.
(Lion Corporation)
Journal Journal of Oleo Science 63 (10) 995-1004, 2014
PMID 25213449

Title A catch-up validation study of an in vitro skin irritation test method using reconstructed human epidermis LabCyte EPI-MODEL24
Author
(affiliation)
Kojima H1, Katoh M2, Shinoda S3, Hagiwara S3, Suzuki T4, Izumi R4, Yamaguchi Y5, Nakamura M5, Kasahawa T6, Shibai A6
(1Japanese Centre for the Validation of Alternative Methods, 2Japan Tissue Engineering Co. Ltd, 3Drug Safety Testing Centre Co. Ltd, 4FANCL Corporation, 5Kobayashi Pharmaceutical Co. Ltd, 6Fujifilm Corporation)
Journal J Appl Toxicol. 2014 Jul;34(7):766-74
PMID 24122860

Title Keratinization induced by air exposure in the reconstructed human epidermal model: an in vitro model of a cultured epithelial autograft.
Author
(affiliation)
Hanada T, Itahara Y, Katoh M, Inoie M, Hata K.
(Japan Tissue Engineering Co., Ltd.)
Journal Journal of Bioscience and Bioengineering 2014 Sep;118(3):323-6

Title Pseudomonas-derived ceramidase induces production of inflammatory mediators from human keratinocytes via sphingosine-1-phosphate
Author
(affiliation)
Oizumi A1, Nakayama H1, Okino N2, Iwahara C1, Kina K1, Matsumoto R1, Ogawa H1, Takamori K1, Ito M2, Suga Y1, Iwabuchi K1,
(1Juntendo University, 2Kyushu University)
Journal PLoS one 25:e89402 (2014)
PMID 24586752

Title Stratum corneum drying drives vertical compression and lipid organization and improves barrier function in vitro
Author
(affiliation)
Iwai I1, Kunizawa N1, Yagi E1, Hirao T1, Hatta I2
(1Shiseido Research Center, 2Spring 8)
Journal Acta Dermato Venereologica 93: 138-143 (2013)
PMID 23165657

Title Photoprotective effects of inclusion complexes of fullerenes with polyvinylpyrrolidone
Author
(affiliation)
Murakami M1, Hyodo S1, Fujikawa Y2, Fujimoto T3,4, Maeda K2
(1Vitamine C60 BioResearch Co., 2Tokyo University of Technology, 3Clinic F, 4Tokai University)
Journal Photodermatology, Photoimmunology and Photomedicine 29: 196-203 (2013)
PMID 23815352

Title Topical surfactant-induced pruritus: involvement of histamine released from epidermal keratinocytes
Author
(affiliation)
Inami Y1,2, Andoh T1, Sasaki A1 and Kuraishi Y1
(1University of Toyama, 2Hoyu Co., Ltd.,)
Journal The Journal of Pharmacology and Experimental Therapeutics 344 (2013) 459-466
PMID 23220712 [PubMed – indexed for MEDLINE]

Title Validation Study of the In Vitro Skin Irritation Test with the LabCyte EPI-MODEL24
Author
(affiliation)
Kojima H1, Ando Y2, Idehara K3, Katoh M4, Kosaka T5, Miyaoka E6, Shinoda S7, Suzuki T8, Yamaguchi Y9, Yoshimura I6, Yuasa A10, Watanabe Y11 and Takashi Omori12
(1Japanese Centre for the Validation of Alternative Methods, 2Aiken Co. Ltd, 3Daicel Corporation, 4Japan Tissue Engineering Co. Ltd, 5The Institute of Environmental Toxicology, 6Tokyo University of Science, 7Drug Safety Testing Centre Co. Ltd, 8Fancl Corporation, 9Kobayashi Pharmaceutical Co. Ltd, 10Fujifilm Corporation, 11Maruishi Pharmaceutical Co. Ltd, 12Doshisha University)
Journal Alternative to Laboratory Animals (ATLA), 40, 22-50 (2012)
PMID 22558976

Title Changes in ceramides and glucosylceramides in mouse skin and human epidermal equivalents by rice-derived glucosylceramide
Author
(affiliation)
Shimoda H1, Terazawa S1, Hitoe S1, Tanaka J1, Nakamura A2, Matsuda H2 and Yoshikawa M2
(1Oryza Oil and Fat Chemical Co. Ltd., 2Kyoto Pharmaceutical University)
Journal Journal of medicinal food., 15(12)2012, 1064-1072
PMID 23216108 [PubMed-in process]

Title Th1 cytokines accentuate but Th2 cytokines attenuate ceramide production in the stratum corneum of human epidermal equivalents: An implication for the disrupted barrier mechanism in atopic dermatitis
Author
(affiliation)
Sawada E1, Yoshida N2, Sugiura A1 and Imokawa G1,3
(1Tokyo University of Technology, 2Ikeda Mohando Co., Ltd., 3Chubu University)
Journal Journal of Dermatological Science 68 (2012) 25-35
PMID 22884781[PubMed- in process]

Title A reconstructed human epidermal keratinization culture model to characterize ceramide metabolism in the stratum corneum
Author
(affiliation)
Yoshida N1,2, Sawada E1 and Imokawa G1
(1Tokyo University of Technology, 2Ikeda Mohando Co., Ltd.)
Journal Archives of Dermatological Research (2012) 304: 563-577
PMID 22451348 [Pubmed-in process]

Title Lack of promoting effect of titanium dioxide particles on chemically-induced skin carcinogenesis in rats and mice
Author
(affiliation)
Sagawa Y1, Futakuchi M1, Xu J1, Fukamachi K1, Sakai Y1, Ikarashi Y2, Nishimura T2, Suzuki M1, Tsuda H1, Morita A1.
(1Nagoya City University, 2National Institute of Health Science)
Journal The Journal of Toxicological Sciences. 2012, 37(.2): 317-327
PMID 22467022 [PubMed-in process]

Title Podoplanin expression in wound and hyperproliferative psoriatic epidermis: Regulation by TGF-β and STAT-3 activating cytokines, INF-γ, IL-6, and IL-22
Author
(affiliation)
Honma M, Minami-Hori M, Takahashi H, Iizuka H
(Asahikawa Medical University)
Journal Journal of Dermatological Science, 2012, 65, 134-140
PMID 22189341 [PubMed-in process]

Title Eucalyptus increases ceramide levels in keratinocytes and improves stratum corneum function.
Author
(affiliation)
Ishikawa J, Shimotoyodome Y, Chen S, Ohkubo K, Takagi Y, Fujimura T, Kitahara T, Takema Y.
(Kao Corporation)
Journal International Journal of Cosmetic Science, 2012, 34, 17-22
PMID 21696405 [PubMed -in process]

Title Prediction of Percutaneous Absorption in Human Using Three-Dimensional Human Cultured Epidermis LabCyte EPI-MODEL 
Author
(affiliation)
Hikima T, Kaneda N, Matsuo K, Tojo K.
(Kyushu Institute of Technology)
Journal Biological and Pharmaceutical Bulletin 2012, 35(3):362-368
PMID 22382322 [PubMed -in process]

Title Skin Irritation Caused by Alcohol-Based Hand Rubs 
Author
(affiliation)
Yamamoto N.
(NOF Corporation)
Journal Infection Control – Updates, ISBN: 978-953-51-0055-3
URL http://www.intechopen.com/books/infection-control-updates/skin-irritation-caused-by-alcohol-based-hand-rubs

Title Refinement of LabCyte EPI-MODEL24 Skin Irritation Test Method for Adaptation to the Requirements of OECD Test Guideline 439
Author
(affiliation)
Katoh M., Hata K.
(Japan Tissue Engineering Co., Ltd.)
Journal Alternatives to Animal Testing and Experimentation (AATEX) 16(3), 111-122 (2011)
PDF https://www.jstage.jst.go.jp/article/aatex/16/3/16_3_111/_pdf

Title Lack of promoting effect of titanium dioxide particles on ultraviolet B-initiated skin carcinogenesis in rats.
Author
(affiliation)
Xu J1,5. Sagawa Y2. Futakuchi M1. Fukamachi K1. Alexander DB1,5. Furukawa F3. Ikarashi Y4. Uchino T4. Nishimura T4. Morita A2. Suzui M1. Tsuda H5.
(1Department of Molecular Toxic Nagoya City University, 2Department of Dermatology, Nagoya City University, 3Daiyukai Institute of Medical Sciences, Inc., 4Natioal Institute of Health Sciences, 5Laboratory of Nanotoxicology Project Nagoya City University)
Journal Food and Chemical Toxicology 49: 1298-1302 (2011)
PMID 21414375 [PubMed - indexed for MEDLINE]

Title In vitro genotoxicity test approaches with better predictivity: summary of an IWGT workshop.
Author
(affiliation)
Pfuhler S1, Fellows M2, van Benthem J3, Corvi R4, Curren R5, Dearfield K6, Fowler P7, Frötschl R8, Elhajouji A9, Le Hégarat L10, Kasamatsu T11, Kojima H12, Ouedraogo G113, Scott A14, Speit G15.
(1The Procter and Gamble Co., 2AstraZeneca, 3National Institute for Public Health and Environment, 4Institute for Health Consumer Protection, 5Institute for In Vitro Sciences Inc., 6Food Safety and Inspection Service, 7Covance Laboratories Limited, 8BfArm, 9Novartis Institute for Biomedical Research, 10Anses, 11Kao Corporation, 12JaCVAM, 13L’Oreal Life Sciences Research, 14Unilever, 15Universidat Ulm)
Journal Mutation Research 723:101-107 (2011)
PMID 21473931 [PubMed - indexed for MEDLINE]

Title Increase in Ceramide Level after Application of Various Sizes of Sphingomyelin Liposomes to a Cultured Human Skin Model.
Author
(affiliation)
Tokudome Y1, Jinno M1, Todo H1, Kon T2, Sugibayashi K1, Hashimoto F.1
(1Josai University, 2Shalom Ltd.)
Journal Skin Pharmacology and Physiology 24(4), 218-223 (2011)
PMID 21447992 [PubMed - as supplied by publisher]

Title Ionic liquid-in-oil microemulsion as a potential carrier of sparingly soluble drug: characterization and cytotoxicity evaluation.
Author
(affiliation)
Moniruzzaman M.1, Tamura M.1, Tahara Y.1, Kamiya N.1,2 and Goto M.1,2
(11Graduate School of Engineering, Kyushu University, 2Kyushu University)
Journal International Journal of Pharmaceutics 400 (1-2), 243-250 (2010)
PMID 20813174 [PubMed - in process]

Title REVIEW
Evaluation of Anti-inflammatory and Anti-allergic Effects of Food Components Using DNA Microarray Analysis
Author
(affiliation)
Kobori M1., Nagai K1,2., Takahashi Y1., Oike H1.
(1National Food Research Institute, 2Mitsubishi Rayon Co., Ltd.)
Journal Japan Agricultural Research Quarterly 44(3), 243-248 (2010)

Title Preferential induction of endothelin-1 in a human epidermal equivalent model by narrow-band ultraviolet B light sources
Author
(affiliation)
Noborio R., Morita A.
(Nagoya City University of Medical Sciences)
Journal Photodermatology, Photoimmunology and Photomedicine 26(3), 159-61 (2010)
PMID 20584257 [PubMed - in process]

Title Assessment of the human epidermal model LabCyte EPI-MODEL for In vitro skin corrosion testing according to the OECD test guideline 431
Author
(affiliation)
Katoh M., Hamajima F., Ogasawara T., Hata K.
(Japan Tissue Engineering Co., Ltd.)
Journal The Journal of Toxicological Sciences 35 (3), 411-417 (2010)

Title The Unfolded Protein Response Is Activated in Differentiating Epidermal Keratinocytes
Author
(affiliation)
Sugiura K1, Muro Y1, Futamura K1,2, Matsumoto K2, Hashimoto N2, Nishizawa Y1, Nagasaka T1, Saito H2, Tomita Y1, Usukura J3.
(1Nagoya University Graduate School of Medicine, 2National Research Institute of Child Health & Development, 3Nagoya University)
Journal Journal of Investigative Dermatology 129 (9), 2126-2135 (2009)
PMID 19282840 [PubMed - indexed for MEDLINE]

Title Morphological Characterization of a Reconstructed, Cultured Human Epidermal Model (LabCyte EPI-MODEL) As an Alternative to in Vivo Models
Author
(affiliation)
Katoh M., Kubo K., Hamajima F., Ogasawara T., Hata K.
(Japan Tissue Engineering Co., Ltd.)
Journal Alternatives to Animal Testing and Experimentation (AATEX) 14 (2), 873-878 (2009)

Title Effect of topically applied sphingomyelin-based liposomes on the ceramide level in a three-dimensional cultured human skin model.
Author
(affiliation)
Tokudome Y, Uchida R, Yokote T, Todo H, Hada N, Kon T, Yasuda J, Hayashi H, Hashimoto F, Sugibayashi K.
(Josai University)
Journal Journal of Liposome Research 20(1), 49-54 (2010)
PMID 19555158 [PubMed - as supplied by publisher]

Title Trypsin as a novel potential absorption enhancer for improving the transdermal delivery of macromolecules
Author
(affiliation)
Li YZ.1, Quan YS.2,3, Zang L.2, Jin MN.2, Kamiyama F.3, Katsumi H.2, Tsutsumi S.1, Yamamoto A.2
(1Kyoto University, 2Kyoto Pharmaceutical University, 3CosMED Pharmaceutical Co. Ltd)
Journal Journal of Pharmacy and Pharmacology 61 (8), 1005-1012 (2009)
PMID 19703343 [PubMed - indexed for MEDLINE]

Title Assessment of human epidermal model LabCyte EPI-MODEL for in vitro skin irritation testing according to European centre for the validation of alternative methods (ECVAM)-Validated Protocol
Author
(affiliation)
Katoh M., Hamajima F., Ogasawara T., Hata K.
(Japan Tissue Engineering Co., Ltd.)
Journal The Journal of Toxicological Sciences 34 (3), 327-334 (2009)
PMID 19483386 [PubMed - indexed for MEDLINE]

Title Dichotomous effect of ultraviolet B on the expression of corneodesmosomal enzymes in human epidermal keratinocytes
Author
(affiliation)
Nin M., Katoh N., Kokura S., Handa O., Yoshikawa T., Kishimoto S.
(Kyoto Prefectural University of Medicine)
Journal Journal of Dermatological Science 54 (1), 17-24 (2009)
PMID 19118981 [PubMed - indexed for MEDLINE]

Title The development of a filter to enhance the efficacy and safety of excimer light (308 nm) therapy.
Author
(affiliation)
Kobayashi K.1, Yasuda Y.1, Shintani Y.1, Sumitomo T.2, Saga T.2, Kimura M.2, Yamamoto A.3, Mori T.3, Maeda A.1, Yamaguchi Y.1, Morita A.1
(1Nagoya City University, 2Ushio Inc., 3Nara Medical University)
Journal Photodermatology, Photoimmunology & Photomedicine 25 (1), 30-36 (2009)
PMID 19152513 [PubMed - indexed for MEDLINE]

Title Evaluation of the skin irritation using a DNA microarray on a reconstructed human epidermal Model
Author
(affiliation)
Niwa M.1, Nagai K. 2,3, Oike H.2, Kobori M.2
(1Katakura Chikkarin Co., Ltd., 2National Food Research Institute, 3Mitsubishi Rayon Co., Ltd.)
Journal Biological & Pharmaceutical Bulletin 32 (2), 203-208 (2009)
PMID 19182376 [PubMed - indexed for MEDLINE]

Title Test Method for Skin Damage of Titania Photocatalyst Nanoparticles in vitro.
Author
(affiliation)
Watanabe E., Fukaya M., Nishizawa K., Miki T., Taoda H.
(National Institute of Advanced Industrial Science and Technology Chubu)
Journal Material Science Forum 569, 9-12 (2008)
URL http://www.ttp.net/0-87849-472-3/toc.html

Title Change in optical properties of stratum corneum induced by protein carbonylation in vitro.
Author
(affiliation)
Iwai I.1, Ikuta K.1, Murayama K.2, Hirao T.1
(1Shiseido Life Science Research Center, 2Gifu University)
Journal International Journal of Cosmetic Science 30 (1), 41-46 (2008)
PMID 18377629 [PubMed - indexed for MEDLINE]

Title Study on the prediction of human lip irritation from cosmetics materials using HeLa-MTT assay.
Author
(affiliation)
Morinaga M., Shingaki K., Mori T., Yanagihara K.
(NOEVIR Co., Ltd.)
Journal Alternatives to Animal Testing and Experimentation (AATEX) 14 (Special Issue), 415-416 (2008)

Title LEDGF/DFS70, a major autoantigen of atopic dermatitis, is a component of keratohyalin granules
Author
(affiliation)
Sugiura K.1, Muro Y.1, Nishizawa Y.1, Okamoto M.1, Shinohara T.2, Tomita Y.1, Usukura J.1
(1Nagoya University Graduate School of Medicine, 2University of Nebraska Medical Center)
Journal Journal of Investigative Dermatology 127 (1), 75-80 (2007)
PMID 16858421 [PubMed - indexed for MEDLINE]

Title Dose-response evaluation using an epidermal model, an alternative to skin irritation testing.
Author
(affiliation)
Kojima H., Ishii I., Nakata S., Konishi H.
(Nippon Menard Cosmetic Co., Ltd)
Journal Alternatives to Animal Testing and Experimentation (AATEX) 11(3), 177-184 (2006)

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CORNEA-MODEL References

Title Upregulated epidermal growth factor receptor expression following near-infrared irradiation simulating solar radiation in a three-dimensional reconstructed human corneal epithelial tissue culture model
Author
(affiliation)
Tanaka Y1., Nakayama J2.,
(1 Clinica Tanaka, 2 Shinshu University.,)
Journal Clinical Interventions in Aging 11, 1027-1033, 2016

Title Establishment of a new in vitro test method for evaluation of eye irritancy using a reconstructed human corneal epithelial model, LabCyte CORNEA-MODEL
Author
(affiliation)
Katoh M., Hamajima F., Ogasawara T., and Hata K.
(Japan Tissue Engineering Co., Ltd.)
Journal Toxicology in Vitro 27, 8, 2184–2192, 2013

Title Morphological characterization of a reconstructed human corneal epithelial model (LabCyte CORNEA-MODEL) as an alternative to the draize eye test for the assessment of eye irritation.
Author
(affiliation)
Katoh M., Uemura N., Hamajima F., Ogasawara T., and Hata K.
(Japan Tissue Engineering Co., Ltd.)
Journal AATEX, 17, (1), 2-8, 2012

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